FOUNDATIONAL LONGEVITY
GSB-02 Grande Super Blend
4.9 out of 5 stars, 9 reviewsLarge dogs don't just age faster, they age differently. GSB-02 is a daily longevity blend clinically validated to support energy levels, cognition, and joint health for big and giant breeds.
Formulated from human longevity research, built to address the underlying causes of aging in dogs.
Large dogs don't just age faster, they age differently. GSB-02 is a daily longevity blend clinically validated to support energy levels, cognition, and joint health for big and giant breeds.
Formulated from human longevity research, built to address the underlying causes of aging in dogs.
For dogs above 35lb / 16kg. For dogs 35lb / 16kg and below, shop ESB-01 →
For dogs above 35lb / 16kg.
For dogs 35lb / 16kg and below, shop ESB-01 →
Each bottle contains a 30-day supply
Delivered by Sep 16
30 day risk free guarantee
PAUSE OR cancel anytime
Free EXPRESS Shipping
- Sustained daily energy
- Improves mood and cognition
- Supports easier movement and joint comfort
- Improves digestion and appetite
- Tested in double-blind placebo controlled study
- NAD+ (via β-Nicotinamide Mononucleotide)
- Pterostilbene
- Resveratrol
- L-carnitine
- Coenzyme Q10
- Glutathione
- Fisetin
- Pyrroloquinoline Quinone (PQQ)
- Spermidine
- d-Alpha-Tocopherol (Vitamin E)
- Third-party tested for quality and allergens
- No refrigeration required
Open 1 capsule and pour over breakfast every morning.
Stories from innovators and members like you
ABOUT GSB-02
The difference healthy aging makes
-
91%
showed a significant increase in energy levels
-
88%
noticed improvements to arthritis and steadier joints
-
84%
saw relief from skin issues and a shinier coat
-
85%
noticed improvements in appetite and better gut health
-
79%
displayed improved heart and kidney function
*Based on a clinical study with 33 dogs (aged 5 - 14) using GSB-02.
Most supplements manage symptoms. GSB-02 addresses aging at the source.
Most supplements manage symptoms. GSB-02 addresses aging at the source.
In large breeds, the mechanisms of aging start earlier and move faster. The window to act isn't when they slow down, it's while the underlying processes are still within reach.
The GSB-02 journey:
Benefits that build over time
Natural repair switches on
GSB-02 starts converting into NAD+ from the first capsule, and their natural repair process switches back on underneath.
Inflammation settles & stiffness eases
Your dog’s inflammation response starts to settle. Stiffness eases, and recovery between walks and play gets quicker.
Cellular fuel shows on the surface
NAD+ has built up enough to give their body real fuel each day. That efficiency starts showing on the surface: softer coat, easier digestion.
Baseline energy & recovery settle in
The changes settle into their baseline. Energy holds steady all day, coat is fuller, digestion is settled, and recovery is quicker.
Long-term cellular resilience
Muscle tone holds, alertness stays sharp, coat keeps improving, recovery stays fast. Immune function runs in better balance. Aging still happens, just slower than it would without the support underneath.
THIS IS WHAT LOVE LOOKS LIKE
Increase in mitophagy flux (LC3-II/LC3-I ratio) vs. placebo
Increase in skeletal muscle NAD+ concentration vs placebo
Improvement in Canine Cognitive Dysfunction Rating (CCDR) score vs placebo
Reduction in serum C-reactive protein vs placebo
Formulated for transformative long-term health.
Enzymatic fermentation origin (nicotinamide + D-ribose pathway), CAS 1094-61-7; stabilised anhydrous form, >98% purity by HPLC
Pterocarpus marsupium (heartwood) extract; trans-isomer, CAS 537-42-8; >99% purity by HPLC; dimethylated stilbenoid analog
Polygonum cuspidatum (Japanese knotweed) extract; trans-isomer, CAS 501-36-0; >98% trans-resveratrol by HPLC; stilbenoid polyphenol isolate
Bacterial fermentation origin, CAS 36687-82-8; tartrate-complexed form, > 97% purity by HPLC
Saccharomyces cerevisiae fermentation origin, CAS 303-98-0; ubiquinone form, >99% purity by HPLC; lipid-soluble benzoquinone
Saccharomyces cerevisiae fermentation origin; CAS 70-18-8; reduced L-glutathione form, >98% purity by HPLC; tripeptide antioxidant isolate
Toxicodendron vernicifluum (Japanese wax tree) extract; CAS 528-48-3; standardized to >98% fisetin by HPLC; flavonoid isolate
Hyphomicrobium sp. fermentation origin, CAS 122628-50-6; disodium salt form, >99% purity by HPLC; redox cofactor isolate
Trihydrochloride Triticum destivum (wheat germ) extract, CAS 334-50-9; standardized polyamine fraction, >98% spermidine by
HPLC
Non-GMO sunflower oil distillate, CAS 59-02-9; natural d-isomer form, >96% purity by HPLC
Shellfish-free
Gluten-free
Poultry-free
Dairy-free
Cattle-free
Allergen-free
No binders
No fillers
No preservatives
Vegan
FDA-Approved labs
Third-party tested
CLINICALLY RECOMMENDED FORMULATIONS
Formulations that provide sustained support using key scientifically and clinically studied ingredients
GSB-02
Grande Super Blend
Starting at $90.00 per month
Fewer supplements. More benefits.
Annual savings
$3,000+
per year when switching to GSB-02
Traditional Supplements
Multivitamins, minerals and antioxidants
$60 USD
Glucosamine
$35 USD
Prebiotics, probiotics, and postbiotics
$30 USD
Omega-3
$45 USD
Chondroitin
$40 USD
Cognitive Support Blend
$45 USD
Vitamin A
$40 USD
Vitamin B9
$45 USD
Total
$340 /mo
vs
Save $250+ /mo
GSB-02 Grande Super Blend
Foundational Longevity
Address aging at the root
- Energy
- Cognition
- Cellular Renewal
- Heart Health
- Joint Support
- Gut Health
Subscription Price
$90 USD /mo
$3.00 USD/day · Monthly subscription
Prices based on average retail cost of individual branded supplements at comparable dosages. The GSB-02 price reflects the % off monthly subscription rate (30-day supply billed $90 USD every month).
How GSB-02 compares:
Targets cellular aging mechanisms
Formulated for prevention, not symptom management
Human-grade, clinically studied ingredient forms and dosages
Independent third-party tested for purity and potency
Formulate specifically for large-breed biology
No fillers, binders, or inactive ingredients
Rigorous testing that meets human standards.
GSB-02 is screened as a full formula for allergens, contaminants and fillers, because what's not in your dog's supplement matters too.
Formulated without shellfish, gluten, dairy and poultry.
Third-party tested for quality and allergens
Manufactured in FDA-registered, GMP-certified facilities
Questions?
We're here to help.
Most owners notice increased energy levels, joint health and coat in as little as 2 to 3 weeks. Other longer term benefits like cardiovascular health and gut immune function may take a little longer. As long as you continue with the daily intake, GSB-02 is doing its work inside to program, sustain, and enhance your dogs health.
Open 1 capsule and pour over breakfast every morning.
Because the signs of aging you see: lower energy, stiffer joints, slower recovery, all trace back to one root cause — your dog's cells gradually losing the ability to repair themselves. In large breeds, that decline arrives faster. GSB-02 works at the cellular level, restoring what the body naturally loses over time and supporting the systems that determine how your dog ages, before the visible signs have a chance to compound.
GSB-02 may be layered or used alone. We've seen it used safely alongside antibiotics, prebiotics, probiotics, fish oils, and other supplements.
GSB-02 is flavorless to blend seamlessly into your dog’s regular meal.
Yes, it is made with human-grade ingredients and without fillers. In fact, the GSB-02 is generally easier on the stomach than many traditional supplements.
No adverse effects on the kidney or liver have been reported at the recommended daily serving.
Both are clinically validated daily longevity peptides built on the same science, but they're formulated for different sized dogs. ESB-01 is made for dogs 35 lb / 16 kg and under, while GSB-02 is made for larger and giant breeds above that weight.The difference in is more than just the dose: Large dogs age faster and through different biology, so GSB-02 keeps the core longevity compounds that benefit every dog and adjusts the rest for large-breed physiology.
